FauxDIS is an educational resource loosely inspired from the FBI’s CODIS database.
Techniques
Techniques
I recently got a WD SN850. There is a little trick to do when you receive it to switch it to 4k LBA and thus getting better performance by using native block size.
tags
nvme
performance
You can have a look at my gitlab and my github account.
These days, I’m mostly programming in Kotlin for backend and data processing, TypeScript for frontend and sometimes in Python, especially for data-exploration and cleaning.
I’m working with ontologies (BFO, OBO-Foundry), semantic-web/linked-data (mainly with RDF4j but also with Jena). In term of database, I favor PostgreSQL and stay away from schema-less nosql DBs except: when I need K/V caching then I use Redis or when I need advanced text-search where I’m going to use Solr and ElasticSearch.
Read More...
Authors:
Adriano Rutz
,
Maria Sorokina
,
Jakub Galgonek
,
Daniel Mietchen
,
Egon Willighagen
,
Arnaud Gaudry
,
James G. Graham
,
Ralf Stephan
,
Roderic Page
,
Jiří Vondrášek
,
Christoph Steinbeck
,
Guido F. Pauli
,
Jean-Luc Wolfender
,
Jonathan Bisson
,
Pierre-Marie Allard
Journal: bioRxiv
Subjects:
Contemporary bioinformatic and chemoinformatic capabilities hold promise to reshape knowledge management, analysis and interpretation of data in natural products research. Currently, reliance on a disparate set of non-standardized, insular, and specialized databases presents a series of challenges to data access, either within the discipline or to integration and interoperability between related domains. The fundamental elements of exchange are referenced structure-organism pairs that establish relationships between distinct molecular structures and the living organisms from which they were identified.
Read More...
,
Maria Sorokina
,
Jakub Galgonek
,
Daniel Mietchen
,
Egon Willighagen
,
Arnaud Gaudry
,
James G. Graham
,
Ralf Stephan
,
Roderic Page
,
Jiří Vondrášek
,
Christoph Steinbeck
,
Guido F. Pauli
,
Jean-Luc Wolfender
,
Jonathan Bisson
,
Pierre-Marie Allard
Journal: bioRxiv
Subjects:
Authors:
David Ribnicky
,
Seon Beom Kim
,
Alexander Poulev
,
Yang Wang
,
Anik Boudreau
,
Ilya Raskin
,
Jonathan Bisson
,
G. Joseph Ray
,
Shao-Nong Chen
,
Allison Richard
,
Jacqueline M. Stephens
,
Guido F. Pauli
Journal: Journal of Natural Products (RoMEO status: White)
Subjects:
Two new diprenylated coumaric acid isomers (1a and 1b) and two known congeners, capillartemisin A (2) and B (3), were isolated from Artemisia scoparia as bioactive markers using bioactivity-guided HPLC fractionation. Their structures were determined by spectroscopic means, including 1D and 2D NMR methods and LC-MS, with their purity assessed by 1D 1H pure shift qNMR spectroscopic analysis. The bioactivity of compounds was evaluated by enhanced accumulation of lipids, as measured using Oil Red O staining, and by increased expression of several adipocyte marker genes, including adiponectin in 3T3-L1 adipocytes relative to untreated negative controls.
Read More...
,
G. Joseph Ray
,
Shao-Nong Chen
,
Allison Richard
,
Jacqueline M. Stephens
,
Guido F. Pauli
Journal: Journal of Natural Products (RoMEO status: White)
Subjects: